| 黄元礼,柯林楠,赵丹妹,王春仁.自愈型水凝胶制备原理及应用于组织工程产品中的现状[J].中国药事,2019,33(10):1149-1156 |
| 自愈型水凝胶制备原理及应用于组织工程产品中的现状 |
| The Principle of Self-Healing Hydrogel Preparation and Its Application in Tissue Engineering Products |
| 投稿时间：2019-06-21 |
| DOI：10.16153/j.1002-7777.2019.10.011 |
| 中文关键词: 自愈型水凝胶 组织工程 医疗器械 |
| 英文关键词: self-healing hydrogels tissue engineering medical devices |
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| 中文摘要: |
| 目的：考察自愈型水凝胶的生产及应用现状，并探讨其在医疗器械领域的应用前景，为开展下一步的研究工作提供参考。方法：通过查阅近年的文献资料，总结自愈型水凝胶包含的不同结构单元的性质，阐述其实现自愈的原理，以及应用于组织工程产品的研究进展，并对其在生物医药领域的应用进行展望。结果与结论：自愈型水凝胶具有良好的自修复性、可降解性及生物相容性，但力学性能不足等问题限制了其在临床中使用。在未来的研究中，通过对结构改性解决现存问题，自愈型水凝胶会在医疗器械领域中具有很好的应用前景。 |
| 英文摘要: |
| Objective: To review the current status of the production and application of self-healing hydrogels, discuss the application prospects of self-healing hydrogels in medical devices and to provide references for the further research work. Methods: By reviewing the literature of recent years, authors of the paper summarized the properties of different structural units contained in self-healing hydrogels and explored the principle of selfhealing, the research progress in tissue engineering products as well as the application of self-healing hydrogels in the field of biomedicine. Results and Conclusion: Self-healing hydrogels have good self-healing property, degradability and biocompatibility. However, due to problems like insufficient mechanical properties, self-healing hydrogels were limited in clinical practice. In future research, self-healing hydrogels will have a good application prospect in the field of medical devices by modifying the structure to solve existing problems. |
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