| 陈家仪,杨耀芳,魏新萍,储继志,金蕾.含毒性成分中成药风湿骨痛胶囊用量合理性分析及对策[J].中国药事,2017,(11):1336-1342 |
| 含毒性成分中成药风湿骨痛胶囊用量合理性分析及对策 |
| Analysis and Countermeasures of Rational Dosage of Chinese Patent Medicine Fengshi Gutong Capsule Containing Poisonous Components |
| 投稿时间：2017-04-07 |
| DOI：10.16153/j.1002-7777.2017.11.020 |
| 中文关键词: 风湿骨痛胶囊 川乌 草乌 用量分析 病案分析 合理用药 中成药在线监测系统 |
| 英文关键词: Fengshi Gutong capsule Aconiti radix Aconiti kusnezoffii radix analysis of dosage case analysis rational drug use online monitoring system for Chinese patent medicine |
| 基金项目:上海市闵行区卫生和计划生育委员会科研课题（编号2015MW39） |
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| 中文摘要: |
| 目的：应用中成药在线监测系统，通过对含毒性中药材"川乌、草乌"风湿骨痛胶囊的用量分析，促进药物合理应用。方法：应用中成药在线监测系统，收集上海市闵行区古美社区卫生服务中心2016年1-6月就诊单使用风湿骨痛胶囊处方的患者病例243例，对其性别、各年龄段的用药情况，包括每日频次、每次剂量、日用药量、总用量、使用天数及复诊用药情况进行分析。结果：每日剂量大于2.4 g有88例（占36.21%）；60~74岁女性患者（60例）多于男性（51例），其中男性（17例）的日剂量（3.02±0.58）g与其余34例的日剂量（2.25±0.26）g相比，有显著性差异（P<0.01）。复诊患者78例，用药量占243例的32.10%；有45例（占18.52%）用法用量正确。结论：开发中成药应用在线监测系统，及时干预应用过程中存在的用量问题，从而促进其合理应用。 |
| 英文摘要: |
| Objective: To analyze the dosage of Fengshi Gutong capsule containing poisonous components, such as Aconiti radix and Aconiti kusnezoffii radix, using online monitoring system for Chinese patent medicine, so as to promote the rational drug use. Methods: A total of 243 patients with prescriptions of Fengshi Gutong capsule in Gumei Community Health Center of Shanghai from January to June, 2016 were collected using the online monitoring system for Chinese patent medicine. The gender of the patients and the following aspects of medication of all age groups were analyzed, including daily frequency, dosage, daily dose, total dosage, medication period and medication of re-visiting patients. Results: There were 88 patients with a daily dose more than 2.4 g (36.21%). 60 patients were females from 60 to 74 years old, which outnumbered males (only 51 cases). 17 males with a daily dose of (3.02±0.58)g. There was significant difference of the daily dose of (3.02±0.58) g of 17 males compared with (2.25±0.26)g of other 34 males. 78 re-visiting patients consumed 32.10% of total medicine consumption by all 243 patients. Only 45 cases (18.52%) showed correct usage and dosage. Conclusion: The development of the online monitoring system and timely intervention on the dosage problems in the course of medication could promote the rational drug use. |
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