| Objective To study pathogens and drug resistance of infectious diarrhea in children. Methods Retrospectively analysis were made on clinical data of 223 infectious diarrhea children, and their outpatient service and electronic medical records were checked to analyze epidemiological features, pathogens , drug resistance and use of Antimicrobial drugs of infectious diarrhea in children. Results: The incidence rate was 44.93% under 1 year old, 36.32% at 1-2 years old, 6.73% at 3-5 years old, and 12.56% at 6-14 years old. The incidence rate was significantly higher at 1 year old. Other age groups (p=0.0001). The incidence season was mainly in summer, the incidence rate was 51.12%, which was significantly higher than other seasons (p=0.0001), the spring incidence rate was 28.25%, the autumn incidence rate was 7.62%, and the winter season was 13.00%. Among the 223 cases, 110 cases were identified as pathogens, and the positive detection rate was 49.33%. Among them, rotavirus infection accounted for 18.39%, Salmonella infection rate was the same as rotavirus, 18.39%, Escherichia coli infection accounted for 4.04%, Staphylococcus aureus infection accounted for 3.14%, Citrobacter infection accounted for 2.24%. %; adenovirus infection accounted for 2.24%, Pseudomonas aeruginosa infection accounted for 1.35%; Proteus mirabilis infection accounted for 0.89%; Klebsiella pneumoniae infection accounted for 0.45%. The results of bacterial resistance showed that the resistance rates of Salmonella and Escherichia coli to ampicillin, cefazolin, and compound sulfamethoxazole were generally higher, while cefoperazone sulbactam and imipenem cilastatin. More sensitive; Staphylococcus aureus is sensitive to macrolides, vancomycin, linezolid and the like. Conclusion: By analyzing the epidemiological characteristics, pathogens and drug resistance of infectious diarrhea in children, it provides a reference for clinical diagnosis and treatment of infectious diarrhea. |