| 王如梦,杨宏新.荜茇及其有效成分胡椒碱的研究进展[J].中国药事,2021,35(3):350-356 |
| 荜茇及其有效成分胡椒碱的研究进展 |
| Research Progress of Fructus Piperis Longi and its Active Ingredient Piperine |
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| DOI：10.16153/j.1002-7777.2021.03.015 |
| 中文关键词: 荜茇 有效成分 胡椒碱 生物碱 药理作用 |
| 英文关键词: Fructus Piperis Longi effective ingredient piperine alkaloid pharmacology |
| 基金项目:国家自然科学基金(编号 81960772)；内蒙古卫计委项目(编号 201702054) |
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| 中文摘要: |
| 目的：对荜茇及其有效成分胡椒碱药理作用的研究进展进行阐述，为其进一步研究及合理利用提供参考。方法：通过查阅国内外近15年有关荜茇及其有效成分胡椒碱的相关文献，并对其进行整理与归纳。结果：荜茇及其有效成分胡椒碱具有抗癌、抗氧化、抗炎、抗菌、免疫调节、保肝、神经保护等多种药理活性及安全性。结论：通过对荜茇及其有效成分胡椒碱药理作用研究进展的阐述，为进一步研究荜茇及其有效成分胡椒碱的药理作用和安全用药奠定基础，充分发挥荜茇及其有效成分胡椒碱的药用价值及合理开发利用提供理论依据。 |
| 英文摘要: |
| Objective: To review the research progress on the pharmacological effects of Fructus Piperis Longi and its active ingredient piperine, so as to provide reference for its further research and rational utilization. Methods: The related literature about Fructus Piperis Longi and its active ingredient piperine in the past 15 years at home and abroad were reviewed and summarized. Results: Fructus Piperis Longi and its active ingredient piperine were found to have many pharmacological activities and safety, such as anti-cancer, anti-oxidation, anti-inflammation, antibacterial, immune regulation, liver protection, neuroprotection and so on. Conclusion: Baced on the research progress on the pharmacological effects of Fructus Piperis Longi and its active ingredient piperine, it lays a foundation for further study on the pharmacological action and safe use of piperine, its active ingredient. Give full play to the medicinal value of Fructus Piperis Longi and its active ingredient piperine and provide a theoretical basis for rational development and utilization. |
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