| 包秀芳,呼日乐巴根,戴丽丽,白文明,铁龙,清明,白其格其,陈美玲,莲花.红花在蒙药应用中的研究进展[J].中国药事,2024,38(8):945-960 |
| 红花在蒙药应用中的研究进展 |
| Research Pogress of Saffron in the Aplication of Mongolian Mdicine |
| 投稿时间：2024-02-16 |
| DOI：10.16153/j.1002-7777.20240119 |
| 中文关键词: 红花 化学成分 药理作用 综述 |
| 英文关键词: Carthamus tinctorius L chemical component pharmacologic effects review |
| 基金项目: |
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| 中文摘要: |
| 目的：红花为菊科一年生草本植物红花（Carthamu stinctorius L.）的干燥花。作为传统的民族药材，具有很高的开发利用价值，本研究旨在为红花的现代研究提供科学依据，为其新药开发和质量评价提供理论支撑。方法：以“红花”“化学成分”“药理作用”“生物活性”“临床应用”“质量标准”等作为关键词，在中国知网、维普、万方、Pubmed等数据库进行相关检索，对其化学成分、药理作用、临床应用等进行归纳总结。结果：共检索到相关文献200余篇，其中有效文献90余篇。红花中的化学成分主要有黄酮类、生物碱、醌氏查耳酮类、炔类、亚精胺类成分和一些其他类别的化合物；具有抗氧、抗纤维化、保护血管内皮功能、抗凝血等药理作用。在蒙医临床中，红花主要被用于预防和治疗血热病、妇科病、肝病、清热解毒等。结论：当前对于红花的化学成分研究已相对全面，而其药理研究则主要围绕治疗冠心病、心绞痛等方面进行。在蒙医临床治疗中，红花通常与清热解毒类药物联合使用，但目前尚未出现关于其毒副作用的明确报道。 |
| 英文摘要: |
Objective: Saffron is the dried flower of Carthamus tinctorius L, an annual herb of Asteraceaefamily. As a traditional ethnic medicinal herb with high development and utilization value, this study aims toprovide a scientific basis for the modern study of saffron and theoretical support for its new drug developmentand quality evaluation. Methods: Using keywords such as ‘saffron’, ‘chemical composition’, ‘pharmacologicaleffect’, ‘biological activity’ , ‘clinical application’ and ‘quality standards’, etc., relevant searches were conductedon databases of CNKI, Wipo, Wanfang and Pubmed. The chemical composition, pharmacological effect andclinical application of saffron were summarized. Resluts: A total of more than 200 relevant literatures weresearched, of which more than 90 were valid. It was found that the chemical constituents in saffron mainly containflavonoids, alkaloids, quinone chalcones, alkynes, subarginine amines, and some other classes of compounds;they have antioxidant, antifibrotic, protection of endothelial function of the vasculature, anticoagulant and other pharmacological effects. In the clinic of Mongolian medicine, saffron is mainly used for the prevention andtreatment of blood fever, gynaecological diseases, liver diseases, clearing heat and detoxification, etc. Conclusion:The current research on the chemical composition of saffron has been relatively comprehensive, while its pharmacological research mainly focuses on the treatment of coronary heart disease, angina pectoris and other aspects. In the clinical treatment of Mongolian medicine, saffron is usually used in combination with heat-clearing and detoxification drugs, but there is no clear report on its toxic side effects. |
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