| 蒋欢欢,申慧琴,王志秀,王紫监.药物治疗管理服务对冠心病患者的效果分析[J].中国药事,2023,(7):849-856 |
| 药物治疗管理服务对冠心病患者的效果分析 |
| Eff ectiveness Analysis of Medication Therapy Management Services for Patients with Coronary Heart Disease |
| 投稿时间：2022-03-03 |
| DOI：10.16153/j.1002-7777.2023.07.015 |
| 中文关键词: 药物治疗管理 冠心病 效果分析 药学服务 效果评价 |
| 英文关键词: medication treatment management coronary heart disease effectiveness analysis pharmacy services eff ectiveness evaluation |
| 基金项目:河北省卫生健康委2020年政府资助临床医学人才培养项目 （编号 361-1104-JSN-2RDY） |
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| 中文摘要: |
| 目的：探讨药物治疗管理（MTM）对冠心病患者的临床效果和人文效果。方法：将140例冠心病患者随机分为干预组（70例）和对照组（70例），对照组给予常规医疗服务，干预组除常规服务之外， 给予规范的MTM服务。观察二组患者临床效果指标[血压达标率、低密度脂蛋白胆固醇（LDL-C）达标率和药物相关问题（MRPs个数）]和人文指标[药依从性量表（Morisky评分）、满意度、效用值和直观相似尺度（EQ-VAS）]的差异。结果：共有10例患者未完成本次研究，其中干预组3例、对照组7例；入组时二组患者的临床效果指标和人文指标比较无统计学差异。末次随访时，干预组患者的LDL-C达标率（P＜0.05）、Morisky评分（P＜0.01）、满意度（P＜0.01）、效用值（P＜0.05）和EQ-VAS评分（P ＜0.01）均显著高于对照组，MRPs个数显著低于对照组（P＜0.01），血压达标率比较二组无统计学意义（P＞0.05）。结论：MTM可提高冠心病患者用药依从性、满意度、生活质量和LDL-C控制效果，解决MRPs，值得推广。 |
| 英文摘要: |
| Objective: To explore the clinical and humanistic effecti-veness of the medication therapy management (MTM) service in patients with coronary heart disease. Methods: 140 patients with coronary heart disease were randomly divided into an intervention group (70 cases) and a control group (70 cases). Patients in the control group were given routine medical services, patients in the intervention group were given standardized medication treatment management services in addition to routine services. The clinical outcome indicators of the two groups were observed: blood pressure compliance rate, LDL-C compliance rate, and Medication-related Problems (MRPs), and humanistic indicators: differences in Morisky Medication Adherence Scale, (morisky scale), satisfaction, utility level, and EuroqolQroup´s Visual Analogue Scale (EQ-VAS). Results: A total of patients did not complete the study, induding 3 cases in intervention group and 7 cases in control groups; There was no signifi cant diff erence between the two groups in index of clinical eff ect and humanistic at enrollment. At the last follow-up visit, the LDL-C compliance rate (P＜0.05), morisky scale (P＜0.01), satisfaction (P＜0.01), utility level (P＜0.05), as well as EQ-VAS scale (P＜0.01) in intervention group were obviously higher than the control group, the number of MRPs wasobviously lower than the control group (P＜0.01), there was no statistical significant in the blood pressure compliance rate between the two groups. Conclusion: MTM service could increase morisky scale, satisfaction, , life quality and LDL-C control eff ect of patients with coronary heart disease, it could solve MRPs and shall be popularized. |
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