| 石岩,王晓伟,刘薇,程显隆,魏锋,马双成.川贝母药材研究进展[J].中国药事,2023,(3):304-311 |
| 川贝母药材研究进展 |
| Review on the Research Progress of Fritillariae Cirrhosae Bulbus |
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| DOI：10.16153/j.1002-7777.2023.03.008 |
| 中文关键词: 川贝母 植物来源 商品规格 化学成分 药理活性 |
| 英文关键词: Fritillariae Cirrhosae Bulbus botanical origins commodity specifi cation chemical component pharmacological activity |
| 基金项目:国家重点研发计划“中药材净切制关键技术与智能设备研究及应用”(编号 2019YFC1711500)；国家科技重大专项“重大新药创制- 中药组分资源库及产业公共技术服务平台建设”(编号 2018ZX09735-006) |
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| 中文摘要: |
| 目的：对川贝母药材的相关研究进行梳理与归纳，为该类药材的资源开发与研究提供参考。方法：基于历年，尤其是近年来的文献资料，对川贝母药材的来源植物变迁情况进行梳理，对市场常见的商品规格进行总结；根据川贝母药材实际化学成分的种类，分别按照生物碱类和非生物碱类成分分别进行描述；对川贝母药材的主要药理活性进行归纳分类。结果与结论：川贝母药材的植物来源不断变化， 目前有6种植物来源；商品规格主要有松贝、青贝、炉贝、栽培品之分；化学成分以生物碱类成分为主；主要对呼吸系统、抗炎及抗肿瘤方面具有药理活性。对川贝母药材的资源保护与开发及其化学与药理方面的进一步深入研究具有一定的参考价值。 |
| 英文摘要: |
| Objective: To sort out and summarize the Research Progress of Fritillariae Cirrhosae Bulbus in recent years, and provide a reference for the resource development and research of this kind of medicinal materials. Methods: Based on related references, especially ones in recent years, the changes of botanical origins of F. Cirrhosae Bulbus were sorted out, and the common commodity specifi cations in the market were summarized. According to the actual chemical components of F. Cirrhosae Bulbus, the alkaloid components and non-alkaloid components were described respectively; the main pharmacological activities of F. Cirrhosae Bulbus were classified and summarized. Results and Conclusion: The plant sources of F. Cirrhosae Bulbus are constantly changing. At present, there are six plant sources. The commodity specifications mainly include Songbei, Qingbei, Lubei and cultivated medicinal materials. The chemical components are mainly alkaloids. It mainly has pharmacological activities on respiratory system, anti-infl ammatory and anti-tumor. It has certain reference value for further study on resource protection and development of Fritillariae Cirrhosae Bulbus and its chemistry and pharmacology. |
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