| 王双艳,黄德红,徐静逍,段红福.基于Granada-Ⅱ分类法评价临床应用丹红注射液的药物相关问题[J].中国药事,2022,36(11):1315-1321 |
| 基于Granada-Ⅱ分类法评价临床应用丹红注射液的药物相关问题 |
| Evaluation of Drug-related Problems in Clinical Application of Danhong Injection Based on Granada-Ⅱ Classification |
| |
| DOI：10.16153/j.1002-7777.2022.11.015 |
| 中文关键词: 丹红注射液 药物相关问题 Granada-Ⅱ分类法 合理用药 |
| 英文关键词: Danhong injection drug-related problems Granada-Ⅱ classification rational drug use |
| 基金项目: |
|
| 摘要点击次数: 814 |
| 全文下载次数: 390 |
| 中文摘要: |
| 目的：基于Granada-Ⅱ分类法，探讨临床使用丹红注射液的药物相关问题(DRPs)，为促进临床合理应用丹红注射液提供参考。方法：借助医院HIS信息系统，收集并整理从2021年 1 月 1 日至 12 月 31日，襄阳市中医医院应用丹红注射液的所有住院患者病历。以丹红注射液说明书、相关指南、专家共识、指导原则等为评价依据，应用Granada-Ⅱ分类法，从必要性、有效性、安全性三方面对住院患者使用丹红注射液进行研究与评价。结果：1158 例患者使用了丹红注射液，其中201例(21.76%)患者发生 DRPs，累计发生 252 药次，包括 143药次DRP4(疗程过短)，61药次DRP6(重复用药)，32药次DRP2(适应症不适宜)，16药次DRP5(溶媒选择不适)；发生DRPs的科室分布以心病科居多。结论：医生在使用丹红注射液时，应尽量避免与其他含有丹参、红花的药物联用。临床药师应参照基于 Granada-Ⅱ分类法的药物临床应用的 DRPs 分类标准，加强中药注射剂的专项点评，促进临床用药的合理性。 |
| 英文摘要: |
| Objective: To explore the drug-related problems (DRPs) of Danhong injection in clinical use based on Granada-Ⅱ classification, and provide references for the rational application of Danhong injection in clinic. Methods: With the help of the HIS information system of the hospital, the medical records of all inpatients who received Danhong injections in Xiangyang Hospital of Traditional Chinese Medicine, from January 1st to December 31st, 2021 were collected and sorted out. Based on the instructions of Danhong injection, relevant guidelines, expert consensus, and the guiding principles, the Granada-Ⅱ classification method was used to study and evaluate the use of Danhong injection in hospitalized patients from three aspects of necessity, effectiveness and safety. Results: Danhong injection was used by 1158 patients, of which 201 (21.76%) patients developed DRPs, and a total of 252 times of drug use occurred, including 143 drug times of DRP4 (short course of treatment), 61 drug times of DRP6 (repeated medication), 32 drug times of DRP2 (inappropriate indication), and 16 drug times of DRP5 (inappropriate vehicle selection). Most DRPS were found in the Department of Cardiology. Conclusion: When using Danhong injection, doctors should try to avoid combination with other drugs containing Danshen or safflower. Clinical pharmacists should refer to the DRPs classification criteria for clinical application of drugs based on Granada-Ⅱ classification, strengthen the special review of traditional Chinese medicine injections, and promote the rationality of clinical drug use. |
|
查看全文
查看/发表评论 下载PDF阅读器 |
| 关闭 |
|
|
|