文章摘要
郭梦林,信凡雪,李飞娥,杨光洁,王璐楠,陈国松,李娟.基于警示内容为线索的华中科技大学同济医学院附属同济医院高警示药品目录的建立[J].中国药事,2022,36(9):1087-1092
基于警示内容为线索的华中科技大学同济医学院附属同济医院高警示药品目录的建立
Establishment of a High-alert Drug Catalogue of Tongji Hospital Affiliated to Tongji Medical College of Huazhong University of Science and Technology Based on the Clue of the Warning Contents
  
DOI:10.16153/j.1002-7777.2022.09.015
中文关键词: 高警示药品  警示内容  目录  合理应用  用药风险
英文关键词: high-alert drugs  warning contents  catalogue  rational use  medication risks
基金项目:
作者单位
郭梦林 华中科技大学同济医学院附属同济医院,武汉 430030 
信凡雪 华中科技大学同济医学院附属同济医院,武汉 430030 
李飞娥 华中科技大学同济医学院附属同济医院,武汉 430030 
杨光洁 华中科技大学同济医学院附属同济医院,武汉 430030 
王璐楠 华中科技大学同济医学院附属同济医院,武汉 430030 
陈国松 华中科技大学同济医学院附属同济医院,武汉 430030 
李娟 华中科技大学同济医学院附属同济医院,武汉 430030 
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中文摘要:
      针对华中科技大学同济医学院附属同济医院(以下简称我院)历年来医疗不良事件及药品不良反应上报情况,建立与我院实际医疗工作契合的高警示药品目录及警示内容,加强高警示药品临床合理应用。方法:根据美国医疗安全协会(ISMP)公布的高危药品目录、中国药学会医院药学委员会推荐使用的高危药品分级管理策略及目录等资料,查阅药品说明书、相关临床指南,结合文献记载的高警示药品用药风险案例、中国裁判文书网高警示药品相关案例,编写高警示药品目录及其警示内容。根据已发表的高警示药品调查问卷相关文献,制定以警示内容为导向的高警示药品目录。结果:将二百余种药品列入我院高警示药品目录,并将其分为特殊警示级高警示药品和一般警示级高警示药品。特殊警示药品分为11类、6种,一般警示药品分为16类。制定《高警示药品速查手册》,供医务工作者学习,相关内容通过我院临床医务人员组成的专家团队复审。结论:药师通过有效途径建立我院高警示药品目录, 整理警示内容,解临床之惑,把对不良事件的事后处理变为前馈控制,从源头上促进高警示药品的合理应用。
英文摘要:
      Objective: To establish a high-alert drug catalogue and the warning contents consistent with the practical medical work of our hospital based on the reports of the adverse medical events and adverse drug reactions in our hospital through these years so as to strengthen the rational clinical use of high-alert drugs. Methods: The high-alert drug catalogue published by the Institute for Safe Medication Practices (ISMP) and the classification management strategy and catalogue of high-risk drugs recommended by the Pharmaceutical Committee of Chinese Pharmaceutical Association were taken as references and the drug instructions and relevant clinical guidelines were consulted. Combined with the risk cases of high-alert drugs recorded in the literature and related cases of high-alert drugs in China Judgements Online, a high-alert drug catalogue and the warning contents were compiled. Based on the published questionnaires related to high-alert drugs, a high-alert drug catalogue oriented by warning contents was developed. Results: More than two hundred kinds of drugs were included in the catalogue of high-alert drugs in our hospital, which were divided into specialized highalert drugs and general high-alert drugs. There are 11 categories of speciallized high-alert drugs with 6 kinds of drugs included, and there are 16 catagories of general high-alert drugs. The High-Alert Drug Handbook for medical workers to learn was formulated, and the relevant contents were reviewed by the expert team composed of clinical medical staff of our hospital. Conclusion: Pharmacists established a high-alert drug catalogue in our hospital by effective approach, sorted out the warning contents, solved clinical doubts, put the post-treatment of adverse events under feedforward control and promoted the rational use of high-alert drugs from the start.
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