| 李爽,沈巍,金迎伟,袁菱,童德银,贾增永.基于间断时间序列分析江苏省人民医院宿迁分院基本药物监管效果[J].中国药事,2022,36(3):348-354 |
| 基于间断时间序列分析江苏省人民医院宿迁分院基本药物监管效果 |
| Analysis of Supervision Effects on Essential Drugs in Our Hospital Based on Intermittent Time Series |
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| DOI：10.16153/j.1002-7777.2022.03.016 |
| 中文关键词: 间断时间序列 基本药物 监管政策 金额占比 品种占比 药物不良反应 |
| 英文关键词: intermittent time series essential drugs regulatory policies proportion of amount proportion of drug varieties adverse drug reactions |
| 基金项目:江苏省青年医学人才项目(编号 QNRC2016483) |
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| 中文摘要: |
| 目的：评估基本药物监管措施对江苏省人民医院宿迁分院基本药物配备使用的影响。方法：收集 2020年1月至12月我院基本药物使用金额占比、采购金额占比、采购品种占比以及不良反应占比，采用间断时间序列数据的分段回归模型，分析实施基本药物监管前后相关数据的变化趋势。结果：自2020年6月实施基本药物监管后，平均使用金额占比由29.56%上升为33.10%，升幅为11.98%；平均采购金额占比由 30.33%上升为35.95%，升幅为18.51%；平均采购品种占比由42.53%上升为43.57%，升幅为2.44%；平均不良反应占比由0.33%上升为0.40%，升幅为21.21%。监管后较监管前基本药物使用金额占比的上升有统计学差异(β1 +β3 =0.986，P = 0.037)；采购金额占比、采购品种占比以及不良反应占比上升无统计学差异(β1 +β3 =1.073，P = 0.488； β1 +β3 =0.153，P = 0.574； β1 +β3 =0.067，P = 0.525)。结论：实施基本药物监管措施效果明显，可供相关医院借鉴。 |
| 英文摘要: |
| Objective: To evaluate the impact of regulatory measures on the allocation and use of essential drugs in our hospital. Methods: The proportion of consumption sum, purchase amount, purchase varieties and adverse reactions of essential drugs in our hospital from January, 2020 to December, 2020 were collected. The piecewise regression model of intermittent time series data was used to analyze the change trend of relevant data before and after the implementation of essential drug supervision. Results: Since the implementation of essential drug supervision in June, 2020, the proportion of the average consumption amount has increased from 29.56% to 33.10% with an increase of 11.98%; the proportion of average purchase amount has increased from 30.33% to 35.95% with an increase of 18.51%; the proportion of the average purchased varieties has increased from 42.53% to 43.57% with an increase of 2.44%; the average proportion of adverse reactions has increased from 0.33% to 0.40% with an increase of 21.21%. There was a significant difference in the proportion of the sum of money for essential drugs used before and after supervision ( β1 +β3 = 0.986, P = 0.037). There were no significant differences in the proportions of purchase amount, purchased varieties and adverse reactions (β1 +β3 =1.073, P = 0.488; β1 +β3 =0.153, P = 0.574; β1+β3 = 0.067, P = 0.525). Conclusion: The effect of implementing essential drug supervision is obvious, which can serve as references for other hospitals. |
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