文章摘要
徐春丽,杨弘瑞,秦晓改,杨继红.门诊呼吸科抗菌药物处方点评分析及干预前后对比[J].中国药事,2020,34(8):983-987
门诊呼吸科抗菌药物处方点评分析及干预前后对比
Comments on Antibiotics Prescriptions of Respiratory Outpatient and Comparison of Pre- and Post- intervention
  
DOI:10.16153/j.1002-7777.2020.08.020
中文关键词: 门诊呼吸科  抗菌药物  处方点评  干预措施  干预效果  合理用药
英文关键词: department of respiration outpatient  antibiotics  prescription reviews  intervention measures  intervention effects  rational drug use
基金项目:
作者单位
徐春丽 贵州医科大学附属医院, 贵阳 550004 
杨弘瑞 厦门大学经济学院,厦门 361005 
秦晓改 贵州医科大学附属乌当医院,乌当 550000 
杨继红 贵州医科大学附属医院, 贵阳 550004 
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中文摘要:
      目的:了解某三甲医院门诊呼吸科抗菌药物处方规范性、用药适宜性、超常行为及干预后效果, 评估干预措施,探索不合理处方的干预模式。方法:采用回顾性分析方法,随机抽取干预前、干预后门诊呼吸科抗菌药物处方每月200张,按照《处方管理办法》《医院处方点评管理规范(试行)》《北京市医疗机构处方专项点评指南(试行)》《抗菌药物临床应用指导原则》《中国医师药师临床用药指南》 《新编药物学》《临床用药须知》以及药品说明书进行处方点评,对点评结果进行统计分析,并对比干预前后的处方合理性的改进。结果:干预前(1~6月)及干预后7~12月、13~18月、19~24月:不合理处方占总处方比例分别是10.00%,12.41%,8.50%和5.67%;不规范处方占总处方比例分别是7.67%, 8.00%,6.00%,2.75%;用药不适宜处方占总处方比例分别是4.33%,5.33%,2.92%,3.75%;干预后的 19~24月,不合理处方和不规范处方的数量与干预前(1~6月)比较具有显著性差异(P<0.01)。干预前后抗菌药物处方比例为29.68%、27.69%、26.56%、26.64%。结论:本院门诊呼吸科抗菌药物处方存在不规范、用药不适宜现象,但干预后不合理处方数、不规范处方数、不规范及用药不适宜项目、不规范和用药不适宜处方占总处方比例、抗菌药物处方比例均有所下降,处方合理率上升至94.33%,接近卫计委的要求,医师处方行为和药师调剂行为呈持续改进之势,干预措施有效,干预模式可行。
英文摘要:
      Objective: To investigate the antibiotic prescriptions, medication suitability, abnormal behaviors and intervention effects from department of respiration outpatient in a three-grade hospital, and to explore the intervention measures. Methods: The retrospective analysis method, randomly selected from respiratory antibiotics prescriptions of pre- and post- intervention 200 monthly, in accordance with the "prescription management method", "hospital prescription comment on standard management (Trial)", "Guidance for Beijing medical institutions prescription special comments (Trial)", "Guidance for clinical application of antibiotics", "Guidance for Chinese physician pharmacists in clinical medication", "new Pharmacology", "clinical medication notice, a written description of the drug and other relevant laws and regulations, one by one review, statistical analysis the review results. Comparative analysis of the rationality of prescription about pre-and post intervention. Results: From 1 to 6 months pre-intervention, 7 to 12 months, 13 to 18 months, 19 to 24 months post intervention, proportions of unreasonable prescription in total prescription were 10.00%, 12.41%, 8.50%, and 5.67%, respectively. The proportions of nonstandard prescription in total prescriptions were 7.67%, 8.00%, 6.00%, and 2.75%, respectively. The proportions of inappropriate medication prescriptions in total prescription were 4.33%, 5.33%, 2.92%, and 3.75%. From 19 to 24 months post-intervention, the quantity of unreasonable prescription and nonstandard prescription compared with 1 to 6 months pre-intervention, there was significantly different. preand post-Intervention, antimicrobial prescription ratios were 29.68%, 27.69%, 26.56%, and 26.64%. Conclusion: The prescription of antibiotics in the Department of respiratory outpatient in our hospital was not standardized and inappropriate. However, the unreasonable number of prescriptions and proportion of non-standard and inappropriate prescriptions, the proportion of non-standard and inappropriate prescriptions in total prescriptions, the proportion of antibiotics prescriptions all decreased post-intervention. The prescription rate of rational increased 94.33%, to the National Mealth and Family Planming Commission of the people's Republic of China requested and physicians' prescription behavior and pharmacists dispensing behavior was continuous improvement potential, effective intervention. It is worth to be promoted in the hospital of the less developed area.
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