| 王宝华,肇丽梅,朱旭,菅凌燕.莫西沙星82例不良反应报告分析[J].中国药事,2020,34(1):114-120 |
| 莫西沙星82例不良反应报告分析 |
| Analysis of 82 Cases of Adverse Drug Reaction Reports Induced by Moxifloxacin |
| 投稿时间：2019-07-09 |
| DOI：10.16153/j.1002-7777.2020.01.018 |
| 中文关键词: 莫西沙星 不良反应 分析 |
| 英文关键词: moxifloxacin adverse drug reactions analysis |
| 基金项目:辽宁省教育厅科学技术研究项目（编号LK201611） |
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| 中文摘要: |
| 目的：分析莫西沙星药物不良反应的发生规律及其特点，为临床合理使用本药及规避不良反应提供参考。方法：使用国家药品不良反应监测系统调取2014年1月至2018年12月中国医科大学附属盛京医院上报的莫西沙星药物不良反应并进行回顾性分析。结果：共调取莫西沙星药物不良反应82例，不良反应的发生以使用静脉制剂为主（71.95%），所有不良反应报告中有39例（47.56%）发生在用药后24小时内，不良反应累及的器官/系统主要为皮肤黏膜（31.71%）、胃肠系统（30.49%）及神经系统（13.41%），多数不良反应在7天内消失。结论：应加强临床医师使用莫西沙星的规范性，提高对不良反应的监测力度。 |
| 英文摘要: |
| Objective: To analyze the occurrence patterns and the characteristics of adverse drug reactions (ADRs) induced by moxifloxacin in our hospital in order to provide references for the rational use of this drug and prevention of ADR in clinical practices. Methods: The occurrences of ADRs induced by moxifloxacin from January 2014 to December 2018 reported by Shengjing Hospital of China Medical University were collected by using Adverse Drug Reactions Monitoring Network, and a retrospective analysis was performed. Results: A total of 82 cases of ADRs induced by moxifloxacin were collected. Most of the ADRs occurred in patients with intravenous preparations (71.95%). 39 ADRs (47.56%) occurred within 24 hours post administration. Organs/systems involved in ADRs were mainly skin and mucosa (31.71%), gastrointestinal system (30.49%) and nervous system (13.41%). Most of the ADRs disappeared within 7 days. Conclusion: The standardization of clinical use of moxifloxacin and the monitoring of ADRs should be strengthened. |
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