| 苏畅,杜晓娟,刘雪婷,宋潇潇,王洋,王淑红,王铁杰.砂仁药材及其饮片的质量分析[J].中国药事,2018,32(11):1483-1489 |
| 砂仁药材及其饮片的质量分析 |
| Quality Analysis on Fructus Amomum and Its Prepared Slices |
| 投稿时间：2018-07-18 |
| DOI：10.16153/j.1002-7777.2018.11.006 |
| 中文关键词: 砂仁 法定标准检验 质量标准提高 DNA条形码 相关性研究 |
| 英文关键词: Fructus Amomum legal standards the improvement of quality standards DNA barcode correlation analysis |
| 基金项目: |
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| 摘要点击次数: 992 |
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| 中文摘要: |
| 目的：对国内市售砂仁质量进行评价分析，为药品监管和质量标准提高提供科学依据。方法：依据法定标准对样品进行全面检验；采用性状和DNA条形码相结合对样品进行真伪评价，以此结果进一步对正品和伪品的挥发油总量和乙酸龙脑酯含量进行相关性分析。结果：按照法定标准抽检的样品，不符合规定项目为性状、乙酸龙脑酯含量测定，以近缘物种冒充砂仁的情况较为突出。结论：国内市售砂仁质量有待提高，可通过质量标准提高，增加专属性较强且可量化评判的性状特征、DNA条形码鉴别等方法进行质量控制。 |
| 英文摘要: |
| Objective: To evaluate and analyze the quality of domestic Fructus Amomum and to lay a scientific basis for drug regulation and the improvement of quality standards. Methods: Samples were thoroughly tested according to the legal standards. Traits and DNA barcode were combined to verify the authenticity of the samples. Based on the results, total amount of volatile oil of genuine and fake products and the content of borneol acetate have undergone correlation analysis. Results: Traits and the content of borneol acetate were the main unqualified items according to the legal standards, and fruits from close-related species were the adulterants. Conclusion: The overall quality of domestic Fructus Amomum needs to be improved, and the quality control can be achieved by improving the quality standards, adding more specific and quantifiable traits as well as DNA barcode identification and so on. |
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