| 彭姝,张军,李慧芬,任重远,马爱霞,张伟.输液中不溶性微粒的危害综述[J].中国药事,2018,32(8):1058-1063 |
| 输液中不溶性微粒的危害综述 |
| A Review of Hazards of Insoluble Particles in Infusion |
| 投稿时间：2018-04-24 |
| DOI：10.16153/j.1002-7777.2018.08.08 |
| 中文关键词: 药品标准 输液 不溶性微粒 危害 |
| 英文关键词: drug standards infusion insoluble particles hazards |
| 基金项目:国家药典委员会"基础输液中不溶性微粒及相关因素的研究"（编号2017012） |
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| 中文摘要: |
| 颗粒异物广泛存在于药品中，能够对人体健康产生不同程度的影响，其中输液药品中的不溶性微粒尤其受到各方关注。国家药典委员会组织对基础输液中不溶性微粒进行了研究。本文通过系统检索，文献梳理信息显示：不溶性微粒经静脉血管进入人体可引起静脉炎、肉芽肿、血管栓塞等一系列危害。这对于输液临床用药安全具有警示作用，对于输液类药品质量评估和标准制修订工作也具有参考意义。 |
| 英文摘要: |
| Granular foreign materials exist extensively in medicines and can exert different degrees of impact on human health. Among them, insoluble particles in infusion are particularly concerned by all parties. Chinese Pharmacopoeia Commission organizes a study on the insoluble particles in essential infusions. The results of literature review shows that insoluble particles can cause a series of hazards in human bodies, such as phlebitis, granuloma, and vascular embolism and so on. This paper gives a warning on the clinical drug safety of infusions and also provides a reference for quality assessment and standard revision of infusion drugs. |
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