| 桑蝶,王佳玉.亚胺培南/西司他丁钠致癫痫的临床分析及治疗[J].中国药事,2018,32(7):975-978 |
| 亚胺培南/西司他丁钠致癫痫的临床分析及治疗 |
| Clinical Analysis and Treatment of Epilepsy Induced by Imipenem/Cilastatin Sodium |
| 投稿时间：2017-05-31 |
| DOI：10.16153/j.1002-7777.2018.07.021 |
| 中文关键词: 亚胺培南/西司他丁钠 癫痫 肺癌 肺部感染 |
| 英文关键词: Imipenem/Cilastatin Sodium epilepsy lung cancer pulmonary infection |
| 基金项目: |
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| 中文摘要: |
| 目的：探讨亚胺培南/西司他丁钠致癫痫发作的防治措施。方法：从1例肺癌合并肺部感染患者使用亚胺培南/西司他丁钠临床病例出发，结合文献分析癫痫的发生机制及治疗方案。结果：该例患者用药结束6小时癫痫发作，给予地西泮10 mg肌注及停药处理，癫痫缓解。结论：癫痫为亚胺培南/西司他丁钠神经系统严重不良反应之一，应加强重视。 |
| 英文摘要: |
| Objective:To explore the prevention and treatment of epilepsy induced by Imipenem/Cilastatin Sodium. Methods:One clinical case was selected of a patient with lung cancer accompanied with pulmonary infection who was given Imipenem/Cilastatin Sodium. The occurrence mechanism and therapeutic method of epilepsy were analyzed based on the literature review. Results:The patient suffered the epilepsy six hours after Imipenem/Cilastatin Sodium was used. After 10 mg diazepam was given through intramuscular injection and Imipenem/Cilastatin Sodium was stopped, the patient's epilepsy was relieved. Conclusion:Epilepsy is one of the serious adverse reactions of Imipenem/Cilastatin Sodium in the nervous system and proper importance should be attached to it. |
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