文章摘要
桑蝶,王佳玉.亚胺培南/西司他丁钠致癫痫的临床分析及治疗[J].中国药事,2018,32(7):975-978
亚胺培南/西司他丁钠致癫痫的临床分析及治疗
Clinical Analysis and Treatment of Epilepsy Induced by Imipenem/Cilastatin Sodium
投稿时间:2017-05-31  
DOI:10.16153/j.1002-7777.2018.07.021
中文关键词: 亚胺培南/西司他丁钠  癫痫  肺癌  肺部感染
英文关键词: Imipenem/Cilastatin Sodium  epilepsy  lung cancer  pulmonary infection
基金项目:
作者单位E-mail
桑蝶 北京市朝阳区三环肿瘤医院, 北京 100122  
王佳玉 中国医学科学院肿瘤医院, 北京 100021 wangjiayu8778@sina.com 
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中文摘要:
      目的:探讨亚胺培南/西司他丁钠致癫痫发作的防治措施。方法:从1例肺癌合并肺部感染患者使用亚胺培南/西司他丁钠临床病例出发,结合文献分析癫痫的发生机制及治疗方案。结果:该例患者用药结束6小时癫痫发作,给予地西泮10 mg肌注及停药处理,癫痫缓解。结论:癫痫为亚胺培南/西司他丁钠神经系统严重不良反应之一,应加强重视。
英文摘要:
      Objective:To explore the prevention and treatment of epilepsy induced by Imipenem/Cilastatin Sodium. Methods:One clinical case was selected of a patient with lung cancer accompanied with pulmonary infection who was given Imipenem/Cilastatin Sodium. The occurrence mechanism and therapeutic method of epilepsy were analyzed based on the literature review. Results:The patient suffered the epilepsy six hours after Imipenem/Cilastatin Sodium was used. After 10 mg diazepam was given through intramuscular injection and Imipenem/Cilastatin Sodium was stopped, the patient's epilepsy was relieved. Conclusion:Epilepsy is one of the serious adverse reactions of Imipenem/Cilastatin Sodium in the nervous system and proper importance should be attached to it.
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