| 鲍方名,沈海英.水分活度与非无菌药品微生物控制[J].中国药事,2018,32(7):913-918 |
| 水分活度与非无菌药品微生物控制 |
| Water Activity and Microbial Control of Non-sterile Drugs |
| 投稿时间：2017-08-18 |
| DOI：10.16153/j.1002-7777.2018.07.012 |
| 中文关键词: 水分活度 非无菌药品 微生物控制 |
| 英文关键词: water activity non-sterile drugs microbial control |
| 基金项目: |
|
| 摘要点击次数: 1635 |
| 全文下载次数: 1949 |
| 中文摘要: |
| 目的：通过控制非无菌药品的水分活度来控制微生物。方法：通过水分活度的概念和各种微生物的最低生长水分活度寻找控制微生物的途径。结果与结论：通过干燥除水、剂型改造、添加组分和降低温度等方法降低水分活度来提高非无菌药品的稳定性。 |
| 英文摘要: |
| Objective:To control microbes by controlling the water activity of non-sterile drugs. Methods:The concept of water activity and the water activities of minimal growth of various microorganisms were discussed to find ways to control microorganisms. Results and Conclusion:The stability of non-sterile drugs could be improved by the following methods to reduce the water activity, such as drying and dehydration, changing the dosage form, adding the components and lowering the temperature. |
|
查看全文
查看/发表评论 下载PDF阅读器 |
| 关闭 |