文章摘要
傅孟元,王壮飞,马元元,周越,管晓东,史录文.国际合理用药评价指标研究概述[J].中国药事,2018,32(4):538-545
国际合理用药评价指标研究概述
Review of International Assessment Indicators of Rational Drug Use
投稿时间:2017-10-12  
DOI:10.16153/j.1002-7777.2018.04.019
中文关键词: 合理用药  评价指标  宏观标准  微观标准  潜在不适当处方  综述
英文关键词: rational drug use  assessment indicator  macro standards  micro standards  potentially inappropriate prescription  review
基金项目:
作者单位E-mail
傅孟元 北京大学药学院, 北京 100191  
王壮飞 北京大学药学院, 北京 100191  
马元元 北京大学药学院, 北京 100191  
周越 北京大学药学院, 北京 100191  
管晓东 北京大学药学院, 北京 100191
北京大学医药管理国际研究中心, 北京 100191 
 
史录文 北京大学药学院, 北京 100191
北京大学医药管理国际研究中心, 北京 100191 
shilu@bjmu.edu.cn 
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中文摘要:
      目的:整理国内外合理用药评价指标,为构建科学的合理用药评价体系提供思路。方法:通过检索中国知网、万方、Pubmed和Proquest等数据库,对有关合理用药评价的文献进行归纳、分析,总结目前国内外有关合理用药的评价指标。结果:合理用药评价的宏观标准包括世界卫生组织不合理用药指标、医院处方点评管理规范等。微观标准主要为潜在不适当处方(PIP)指标,其中明确标准包括比尔斯标准(Beers)、老年人不适当处方和处方遗漏筛查工具(STOPP/START)、虚弱老年人治疗评估标准(ACOVE)、中国老年人疾病状态下潜在不适当用药初级判断标准等;隐含式标准包括处方优化方法、药物合理指数等。结论:无论是宏观还是微观标准都是很好的处方评价工具,但研究者在实际应用中需要关注每个标准中指标设置的理由和建议,根据不同标准的特点,充分考虑评价对象、数据特征、药品目录、地区用药习惯等因素,对评价工具进行选择和调整。
英文摘要:
      Objective: To sort out the assessment indicators of rational drug use at home and abroad so as to provide ideas for establishing a scientific evaluation system for rational drug use. Methods: China National Knowledge Infrastructure (CNKI), Wanfang, PubMed and Proquest databases were searched and the literatures about the assessment of rational drug use were summarized and analyzed to fnd the current assessment indicators relevant to rational drug use at home and abroad. Results: The macro standards for assessment of rational drug use include the irrational drug use indicators of World Health Organization, hospital prescription reviews and management practices, etc. The micro standards are mainly potentially inappropriate prescribing (PIP) criteria, which explicitly include the Beers criteria, the STOPP/START criteria, the ACOVE criteria, the primary standards of potentially inappropriate medication in Chinese aged people under morbid state, etc. The implicit standards include the prescription optimization method, the medicine appropriateness index, etc. Conclusion: Both macro and micro standards are good prescription assessment tools. However, the researchers are supposed to pay attention to the reasons and recommendations of the indicators set in each criterion, and take full account of the subject, data characteristics, drug catalog, regional medication habits and other factors, and then select and adjust the assessment tools according to the characteristics of different standards.
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