| 朱炯,吴建敏,黄海伟,刘毅.差示扫描量热法在药品检验中的研究进展[J].中国药事,2018,32(2):210-215 |
| 差示扫描量热法在药品检验中的研究进展 |
| Research Progress of Differential Scanning Calorimetry in Drug Testing |
| 投稿时间：2017-02-07 |
| DOI：10.16153/j.1002-7777.2018.02.009 |
| 中文关键词: 差示扫描量热法 纯度 晶型 熔点 热稳定性 应用 |
| 英文关键词: DSC purity crystal structure melting-point thermal stability application |
| 基金项目:国家科技重大专项“重大新药创制”（编号2015ZX09303001）；中国食品药品检定研究院学科带头人培养基金（编号2015X3） |
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| 中文摘要: |
| 差示扫描量热分析（DSC）具有简便快速、重现性好、且避免繁杂的样品制备过程等优点。本文着重综述了近年来DSC在包括纯度测定、晶型表征、熔点检测、热稳定性检查和中药定性定量分析等药品质量控制研究中的多方面应用进展情况，并展望了其未来发展前景。 |
| 英文摘要: |
| Differential scanning calorimetry (DSC) has the advantages of being simple, rapid, having good reproducibility, and requiring no sample preparation. The progress of the application of DSC in drug quality control, including purity determination, crystal structure characterization, melting-point detection, thermal stability test, as well as qualitative and quantitative analysis of traditional Chinese medicine was reviewed in this paper. The future development prospect was also discussed. |
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