张南平,余坤子,魏锋,马双成.中药材质量的本质与评价方法探讨[J].中国药事,2018,32(1):48-53 |
中药材质量的本质与评价方法探讨 |
On the Quality Essence and Evaluation Method of Traditional Chinese Medicinal Materials |
投稿时间:2017-05-08 |
DOI:10.16153/j.1002-7777.2018.01.009 |
中文关键词: 中药材 质量 评价 质量本质 道地药材 指纹图谱 |
英文关键词: traditional Chinese medicinal materials quality evaluation quality essence genuine medicinal materials fingerprint |
基金项目:国家新兴产业重大工程包中药标准化项目“槟榔等20种中药饮片标准化建设”(编号ZYBZH-Y-GD-13) |
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中文摘要: |
目的:为传统中药材质量评价及标准制订提供概念上的依据。方法:从中医药学的发展过程及影响中药材药性和质量的诸多因素,对中药材的质量本质以及与天然药物的关系、“地道药材”产生的人文及生态原因作一些探讨。结果:中药材和民间药虽然都是天然药物,作为药物,其性质有时是完全不同的,中药材是在传统中医理论指导下使用的药物,其质量评价方法也应根据传统质量评价情况与天然药物或民间药物区别对待。结论:中药材具有明确的药性(药效谱)、较好的性状质量、较高的有效成分含量,以及稳定的各成分比例关系,“道地药材”就是其中的典型代表。天然药物和民间药是属于辨病用药的药物,而不是中医的辨证用药。本文根据中药材质量的内涵,提出指纹图谱结合成分权重的质量评价模式用于评价中药材的质量。 |
英文摘要: |
Objective: To lay a conceptual basis for the quality evaluation and the standard formulation of traditional Chinese medicinal materials. Methods: Discussions were carried out on the quality essence of traditional Chinese medicinal materials and its relations with natural medicines as well as human and ecological reasons for the formation of the "genuine medicinal materials" according to the historical development of traditional Chinese medicines and the factors which affect the property and quality of the traditional Chinese medicinal materials. Results: Traditional Chinese medicinal materials are natural medicines like folk medicines, but their natures are sometimes completely different. Chinese herbal medicines are used under the guidance of traditional Chinese medicine theory, therefore their quality evaluation methods should also be based on traditional quality assessment, different from natural medicines or folk medicines. Conclusion: Chinese medicinal materials have definite property of medicine, good quality of traits, highly active ingredient content and stable proportion of ingredients. "Genuine medicinal materials" is one of the typical representatives. Natural medicines and folk medicines are disease-related drugs rather than syndrome differentiation and medication. Based on the connotations of the quality of Chinese medicinal materials, this paper put forward a quality evaluation method,of which the combination of fingerprints and the weight of the ingredients were used to evaluate the quality of Chinese medicinal materials. |
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