文章摘要
李明真.2013-2015年合肥市第三人民医院中药注射剂使用情况分析及合理性评价[J].中国药事,2017,(3):337-342
2013-2015年合肥市第三人民医院中药注射剂使用情况分析及合理性评价
Analysis and Evaluation of the Utilization of Traditional Chinese Medicine Injections in a Hospital from 2013 to 2015
投稿时间:2016-09-05  
DOI:10.16153/j.1002-7777.2017.03.017
中文关键词: 中药注射剂  评价分析  用药频度  不良反应  药师干预
英文关键词: traditional Chinese medicine injections  analysis and evaluation  DDDs  ADR  pharmacist intervention
基金项目:
作者单位
李明真 合肥市第三人民医院, 合肥 230022 
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中文摘要:
      目的: 分析合肥市第三人民医院2013-2015年中药注射剂的应用情况,为临床合理用药提供参考。方法:通过医院HIS系统,调取中药注射剂的用药数据,对本院中药注射剂的用药品种、金额、用药频度(DDDs)等进行统计,分析其用药规律;对临床药学室收集到的因使用中药注射剂而发生的不良反应病例报告进行整理、分析;利用PASS临床药学管理系统,评价中药注射剂的用药合理性。结果:2013-2015年中药注射剂用药金额分别占全年药品总金额的11.8%、10.5%、10.4%;活血化瘀类中药注射剂的DDDs呈逐年上升趋势,其中,注射用血栓通与注射用血塞通的DDDs排名连续3年居第l位与第2位,其不良反应发生率也连续3年位居前列;理血剂使用最为广泛,每年销售金额占比均超过65%;中药注射剂使用中存在适应证不适宜、用法用量不适宜、联合用药不当、疗程偏长等情况。结论:本院中药注射剂使用基本合理,但也存在不规范之处,有待继续通过临床药师干预、处方医嘱点评、合理用药宣教等手段来进一步规范。
英文摘要:
      Objective: To analyze and evaluate the utilization of traditional Chinese medicine injections in the Third People's Hospital of Hefei from 2013 to 2015, so as to provide references for clinical rational drug use.Methods: The drug utilization data of traditional Chinese medicine injections provided by HIS system of the hospital were collected to statistically analyze the consumption sum, types and DDDs in order to find out the rule of drug use. The reports of adverse drug reactions caused by the use of traditional Chinese medicine injections in clinical pharmacy laboratory were collected and analyzed. The PASS clinical pharmacy management system was used to evaluate the rationality of drug use of traditional Chinese medicine injections. Results: The consumption sum of traditional Chinese medicine injections accounted for 11.8%, 10.5% and 10.4% of the total annual income from 2013 to 2015 respectively. The DDDs of the Chinese patent injections to promote blood circulation and remove blood stasis increased year by year, Xueshuantong and Xuesaitong injection ranked the first and the second place in DDDs for 3 consecutive years, and their incidence of adverse reactions was also in the forefront for 3 consecutive years. The blood agent was used most frequently in the hospital, accounting for more than 65% of the total annual income. During the use of Chinese patent injections, problems, like inappropriate indications, inappropriate usage and dosage, inappropriate combination of drug use, as well as prolonged therapy, could still be found. Conclusion: The utilization of the traditional Chinese medicine injections in the hospital is basically rational. However, some problems still exist, which need further improvement through the intervention by clinical pharmacists, review of prescription and popularization of rational drug use.
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