| 孙立宏.保健食品中降糖药物盐酸二甲双胍的测定[J].中国药事,2017,(1):79-81 |
| 保健食品中降糖药物盐酸二甲双胍的测定 |
| Determination of the Hypoglycemic Drug Metformin Hydrochloride in Health Food |
| 投稿时间：2016-08-02 |
| DOI：10.16153/j.1002-7777.2017.01.015 |
| 中文关键词: 保健食品 化学药物添加 盐酸二甲双胍 检测方法 紫外分光光度法 |
| 英文关键词: health food chemical drug addition metformin hydrochloride detection method UV spectrophotometry |
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| 中文摘要: |
| 目的：建立测定保健食品莱迪康胶囊中化学药品盐酸二甲双胍的方法。方法：采用经典UV-紫外分光光度法，检测波长233 nm。结果：盐酸二甲双胍被测溶液浓度在4.22~8.80 μg·mL-1范围内线性关系良好（r=0.9999，n=6），加标回收率为100.69%，RSD为0.41%。结论：本方法快速、准确、灵敏度高、重复性好，可作为该保健食品中添加化学药品盐酸二甲双胍的有效分析方法。 |
| 英文摘要: |
| Objective: To develop a determination method for metformin hydrochloride in the health food Laidi kang capsule. Methods: The classical ultraviolet UV-spectrophotometric method was used and the detection wavelength was 233 nm. Results: Metformin hydrochloride concentration in the test solution showed a good linear relation within the range of 4.22-8.80 μg·mL-1(r=0.9999, n=6), the standard addition recovery rate was 100.69%, and RSD was 0.41%. Conclusion: This testing method is rapid, accurate, with high sensitivity and good repeatability, and can be used as an effective analytic method for the metformin hydrochloride added in health food. |
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