文章摘要
计文婧,蒋华林,叶丹,刘海英,王卫东,高春燕,刘晶,方宇.孕妇对B族链球菌疫苗的态度和接种意向研究[J].中国药事,2021,35(5):586-594
孕妇对B族链球菌疫苗的态度和接种意向研究
Study on Attitude and Vaccination Intentions of Pregnant Women Towards Group B Streptococcus Vaccine
  
DOI:10.16153/j.1002-7777.2021.05.014
中文关键词: B族链球菌  疫苗  孕妇  健康信念模型
英文关键词: group B streptococcus  vaccine  pregnancy women  health belief model
基金项目:国家自然科学基金(编号 71974156);中国博士后科学基金项目(编号 2020M673427)
作者单位
计文婧 西安交通大学药学院药事管理与临床药学系,西安 710061 
蒋华林 西安交通大学公共卫生学院流行病与卫生统计学系,西安 710061 
叶丹 西安交通大学药学院药事管理与临床药学系,西安 710061 
刘海英 广州市妇女儿童医疗中心检验科,广州 510623 
王卫东 长沙市妇幼保健院医务科,长沙 410007 
高春燕 唐山市妇幼保健院检验科,唐山 063000 
刘晶 清华大学医院检验科,北京 100084 
方宇 西安交通大学药学院药事管理与临床药学系,西安 710061 
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中文摘要:
      目的:调查孕妇对B族链球菌(GBS)疫苗的态度与接种意向,为针对性地提高GBS疫苗接种, 最终控制GBS感染提供参考。方法:选择北京、广州、长沙、西安和唐山5所城市的5个三级医院的孕妇进行横断面问卷调查,内容主要围绕孕妇对GBS感染的认知和对GBS疫苗的态度。调查问卷在健康信念模型和预调查的基础上编制完成,调查对象通过微信扫描二维码获得问卷题目并回答,数据分析主要使用描述性统计方法进行。结果:共932人(86.0%)完成了调查。大多数孕妇(82.8%)担心GBS可以从母亲传染给婴儿。对一种新疫苗的安全性和有效性存在担忧的调查对象分别高达89.9%和86.5%。如果有可用的GBS疫苗,61.6%的调查对象表示“可能”或“一定”选择接种。超过90%的孕妇表示会遵从医生的建议;信念是影响选择是否接种的主要因素。结论:参与本研究的调查对象对新疫苗的安全性和有效性存在一定顾虑,但仍有一半以上表示会选择接种GBS疫苗。此外,信念和医疗保健人员的建议在疫苗接种决策中具有重要的引导作用,因此,制定包括相关专业人员参与的健康教育计划非常必要。
英文摘要:
      Objective: To investigate the attitude and intention of Group B Streptococcus vaccine in pregnant women to provide essential information for the process of the vaccine introduction and eventual control of GBS infection. Method: A cross-sectional questionnaire survey was conducted among pregnant women in five large urban tertiary care hospitals located in Beijing, Guangzhou, Changsha, Xi’an and Tangshan, focusing ontheir perceptions of GBS infection and attitudes toward GBS vaccine. The questionnaire was developed on the basis of the Health Belief Model, and pre-research, and the respondents obtained the questionnaire questions and answered them by scanning the QR code through WeChat, and the data analysis was conducted by using descriptive statistics. Results: A total of 932 pregnant women (86.0%) responded to the survey. Most pregnant women (82.8%) were concerned that GBS could be transmitted from mother to baby. Concerns about the safety and efficacy of a new vaccine were high at 89.9% and 86.5% of respondents respectively, while 61.6% “probably” or “definitely” would get vaccinated in their present pregnancy if available. More than 90% of participants would follow obstetrician/gynecologist suggestions on vaccination. The belief was the most influential factors influencing the choice to vaccinate or not. Conclusion: Pregnant women in this study have concerns about the safety and effectiveness of a new vaccine, but more than half still indicated that they would get vaccinated. In addition, the belief and recommendations from healthcare professionals play a key role in vaccination decision. Therefore, it is necessary to develop a health education plan including the participation of relevant professionals.
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