| 陈涛,付海洋,李岩,付步芳.羟基磷灰石基复合骨修复材料研究进展[J].中国药事,2019,33(3):302-309 |
| 羟基磷灰石基复合骨修复材料研究进展 |
| Research Progress of Hydroxyapatite-based Composite Bone Repair Materials |
| 投稿时间：2018-11-14 |
| DOI：10.16153/j.1002-7777.2019.03.011 |
| 中文关键词: 骨修复 羟基磷灰石 复合材料 载药 |
| 英文关键词: bone repair hydroxyapatite composite materials drug-loading |
| 基金项目:国家重点研发项目（编号2017YFC1105000） |
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| 中文摘要: |
| 羟基磷灰石因为接近骨组织成分，具有优良的生物相容性，而被广泛应用于骨修复领域。由于单一材料不具有多种优异的生物学性能，因此，制备性能优越的羟基磷灰石/聚合物复合骨修复材料成为骨修复材料领域的热点之一。本文综述了设计羟基磷灰石基复合骨修复材料的一些要点，总结了近几年国内外羟基磷灰石/聚合物复合材料的研究状况，并介绍了载药羟基磷灰石骨修复材料的研究情况，最后对羟基磷灰石基复合骨修复材料的发展提出展望。 |
| 英文摘要: |
| Hydroxyapatite is widely used in the field of bone repair because it is similar to bone tissue components and has excellent biocompatibility. Because single material does not have a variety of excellent biological properties, the preparation of hydroxyapatite/polymer-based composite bone repair materials with superior performance has become one of the hotspots in the field of bone repair materials. This paper reviews some key points of designing hydroxyapatite-based composite bone repair materials and summarizes the research status of hydroxyapatite/polymer-based composites at home and abroad in recent years. In addition, this paper introduces the research situation of hydroxyapatite bone repair materials for drug-loading and puts forward some prospects for the future development of hydroxyapatite-based composite bone repair materials. |
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